Ezra Pryor has been in the cannabis industry for the past 6 years since starting EZ Chem Consultancy in 2013. He is Heidolph North America’s Applied Markets Specialist. He is a founding member of the American Chemical Society’s Cannabis Chemistry Subdivision and serves in the ASTM International’s Committee D37 on Cannabis.View the profile
I graduated from the University of Florida with a degree in Chemistry/Biochemistry with undergraduate research in drug design and synthesis. For the first two years of my career I worked in GMP and GMP like environments designated for the manufacturing of virus, plasmid DNA, oligos, and small molecules, specifically in the downstream purification setting. An opportunity became available for a chemist with purification and scientific documentation experience in the cannabis sphere, which I interviewed for and later accepted as my first processing job. Since then, I have attained hundreds of hands on hours with extracting, refinement, and distillation through various positions/roles.View the profile
Jake Starkey is well versed in laboratory design, cannabinoid extraction technology, and product scaling. His background in manufacturing, education in biochemistry, and years of experience in the legal cannabis industry give him a unique competitive advantage. Over his career he has accumulated a library of intellectual property relating to the 3 main types of solvent extraction with an emphasis on supercritical CO2 extraction.View the profile
John A. MacKay earned his B.A. in Chemistry at the St. Lawrence University. He also earned his Ph.D. At the University of Vermont, where he focused on Inorganic Chemistry and on the synthesis of cancer fighting compounds. After working in teaching positions at the University of Vermont, Lyndon State College, and Davidson College, John went on to join Waters Corporation in 1983.View the profile
About the talk
As explorations of the medicinal applications of cannabinoids extracted from hemp continue to unveil powerful therapeutic alternatives, the demand for pharma-grade molecules likely will increase. This could be, in part, a purification pathway, such that the cannabinoid-powered soup drawn from deconstructed plants can be further fractionated into its individual ingredients. As product formulators continue to recognize the merit of using full- or broad-spectrum products, they can first purify their starting materials such that precise concentrations of each desired ingredient can be added to the designed formulation. Or, those utilizing CBD isolate can refine the starting oils to effectively remove all other chemical ingredients, including heavy metals and residual pesticides that can taint lower grade materials. There are multiple methods for achieving this, including initial product refinement techniques like winterization and activated carbon filtration, each removing an assortment of molecules. To refine even further, options like distillation or supercritical fluid chromatography can be employed. This panel dives in to these methods, including what these options entail, and how they can best be implemented.
Can I just do one type of extraction will take it out? So I have to know if all the mold will come over. Everyone's going to come over when you do CO2 00:00 the mole won't come over. It's not soluble but everything that that mold made before you took it out is an organic molecule 00:07 that's coming over here Alpha and beta aflatoxins that the mold maybe goes will come over and so now you've made yourself a problem. The other one 00:16 that I would say is you're moving towards concentration it if I have something is 10% I'm sorry, but there's not a little man in a little man or 00:26
little person inside there no separating out things. So whatever you have over here with your eminence with all the different colors, and I just 00:35 want the blue will if you concentrate out all the M&M packages on this man in the should have known if you take the package is not going to come over 00:45 then you're still concentrating everyone else. So the PC starts off at point one and you concentrated 10x. 00:53 I'm guessing the numbers come out to 1% Which is higher than .3 last time I and so everything comes over to you have to know all the way to the 01:02
process what comes over so different prophecies will allow you to minimize United THC. Ethanol is not one of them. Can I reiterate your history? 01:12 And he said it but it's very than a lot of other things. He said so I'm going to concentrate. Yeah, and I gave a smartass answer. So I feel like I 01:21 really need to give a better answer so you can purify pesticides out of here make sure it really is going to take in for 01:30 most operations. That's cost prohibitive. You're looking at like starting at around $40,000. So, 01:40
you know me. Penny is it does make sense to get rid of it and don't put it in in the first place and an issue two 01:49 people have is you can contaminate your system with pesticides because you put it in your traction unit, and now you've got cleaning material coming 01:59
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