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An Open Source ANOVA and Power Analysis Tool made in R/Shiny (Marly Gotti, Jake Gagnon)

Marly Gotti
Senior Data Scientist at Biogen
+ 1 speaker
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R/Medicine 2020
August 29, 2020, Online, USA
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About speakers

Marly Gotti
Senior Data Scientist at Biogen
Jake Gagnon
Senior Principal Biostatistician at Biogen

Specialties: Biostatistics, Bioinformatics, Machine Learning, Computational Biology, and Statistical Genetics Current Languages: R (mlr, caret, ggplot, plotly), R-Shiny, Python Dash, Python (sci-kit learn, pandas, numpy, tensorflow, nltk, opencv), bash, and robot operating system (ROS)

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This video is part of the R/Medicine 2020 Virtual Conference.

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Hello everyone. My pleasure to introduce Marley got T&J Kaden. Both some Marley's. A senior data scientist to Biogen and Jake is a senior principal biostatistician. They're going to talk to you about a shiny based a Nova and power analysis tool, please. Who are the status quo Dodge in currently? Is that the decisions often received many requests that resource? I could perform Anova or sample size calculation soccer packages such as prism wish to do not suffer a woman over and over aggressive

Manner and is not perform calculations. LOL. Sometimes all the scientists May perform these and over and houses and correctly, which it may lead to incorrect interpretation for their internal about experiments are. They may use incorrect models or announce the channels and they also have to be careful out on Nova subjects. So it's a lot of assumptions are violated. This may in fact that you guys are the findings. LOL play sample size calculation for a

number two. Large, that's a waste of time and resources. Tell her we're going to be using this so we're hoping to get a nap. So that's what is a little more rigorous than pre-existing tools have scrap that for them. And we're striving to increase that reproducibility. Freaking Apple studies. I'm also hoping to increase the quality for now so that thousand years and streamlining. Are some of the benefits of automation Center Station by streamlining, our calculation for a Nova and power calculation. So, we are now at any results in less than

30 minutes, waiting weeks for the position to do that, over calculations of the Sciences. We're also hoping to empower scientist before, I know who I talk to you. Another advantage over and over at this represent for specific scenarios. And lastly, that over apps off is standardizing posted any important date outfit. Navigate to be mindful of the scope and limits of our apps over the within scope of the actors and over and over of the latest sample size calculation for studies.

Pictures of models. We are, we are allowing a one-way and two-way bottles as well as interaction effects, and no interaction effects, and handling, unfair design. And no, repeated measures and does not support repeated measures Anova. I want to discuss are some of the features of her so that allows the user to import into it. They have also check Scott liars and the user can rule out letters. If they desire then are the user accounts already set up their comparisons of

interest. And then the Apple / those table with adjustable. I want sample size of our calculations. For the commercial power is based on a Formula First for the details, and then I'm here at your car now, sis be fun. Simulation I want is to have automatically suggest a model for the, for the user to use. After, after all the user selects out their interpretation of each other at the user selects, the boss is showing at all this tradition and I am just a normal day.

Elsa want to give you an overview of the powerhouses. I have over 900 within the powerhouses tablet user comes out, use their primary and secondary objectives for the next apple calculate sample, size of her group required, to observe, at least one of their primary hibachis in the next after the desired effect size or 80% power, and 85%. And then, finally the user top of the reports of their Anova powerhouses findings Send The Travelers a user can select it. During the powerhouses tab is the desired effect size of zero, defects

of the user can satisfy their by, their families are rates. And they're expected Motel be great. And if I get to Taco study, the Apple automatically calculates that the variances based on the pilot theater, Diane's house for pharmacist in calculation, based on two users review of the equal equal variance. in addition to the App Store and now I want to hand over We're going to use a lot of lies and deceit. That has three, three main groups. Let's take a look at

the application. Navigation, you have three types of a SWOT analysis. Please problem. Change. Are you going to blow? My default application house at 3. No, I'm looking at your dinner. We're going to be able to be a way for you to tell Now, offered equal 3DS normal, normal or abnormal. Baby culture that has all the points on the diagonal line. And you top open switches a liar top and they stop allowing you to remove all Liars from the Vita sites as well as I'm sorry. We

can see that there are no points greyed out. And if I don't shake stop Bass, music jazz fest. so, these are And so Alyssa like the parish for multiple comparison. While looking at the comparison and results, we can see that x-ray. It's not aesthetically significant change. The value is greater than 45. And I'm running music. Notification throughout has little choices, like, increasing the size of that. That you can take advantage of the keys. Okay, let's go to the sample size calculation chart.

Sample size calculation, software shoes. Now we will or you can see that based on the previous elections disable of effect size on the x-axis or some sample size for displays, actually that the observed facts for the day. Over the size of my wish means that we need 25 animals. We can also take a look. now, I'll be after you have review all the tops you can get in and for the sake of time, And you can take a look at so it actually record of the application and

equation. Google like to interpretation by Michael Farris. Thank you. So, let's see, we have a question that's been upgraded, does the app generate reproducible code for a specific analysis? Analysis has been run. Like that one song, that's a good question. And so far the application does not that we are open for anyone. Have you had a chance to look at any other Anova, our packages, for instance them this one called the do Xbox. What's the news? Well, I don't see any more questions from the audience, but thank you. And, you know, I really think that the you've got a

winner there for that happened. I hope you get lots of users. Great, thanks.

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