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A6 Optimizing Influenza Vaccine Composition: A Machine Learning Approach

Hari Bandi
Doctoral student at Massachusetts Institute of Technology
+ 1 speaker
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Machine Learning for Healthcare
August 7, 2020, Online, Los Angeles, CA, USA
Machine Learning for Healthcare
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Hari Bandi
Doctoral student at Massachusetts Institute of Technology
Dimitris Bertsimas
Professor at Massachusetts Institute of Technology

I am a Ph.D. candidate in Operations Research at MIT, advised by Prof. Dimitris Bertsimas. My primary research interests lie at the interface of Optimization and Machine Learning with applications in Healthcare and Finance. Specifically, I work on designing novel Optimization algorithms for Machine Learning problems using tools from Robust and Discrete Optimization. Prior to joining MIT, I worked at Google Research and IBM T.J. Watson Research Center as a research associate. I earned an Integrated Masters in Mathematics and Computer Science from IIT Kharagpur.

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Dimitris Bertsimas is the Boeing Leaders for Global Operations Professor of Management, a Professor of Operations Research, and the Associate Dean for the Master of Business Analytics at MIT. A faculty member since 1988, his research interests include optimization, stochastic systems, machine learning, and their application. In recent years, he has worked in robust optimization, statistics, healthcare, transportation and finance. Bertsimas was a cofounder of Dynamic Ideas, LLC, which developed portfolio management tools for asset management. In 2002, the assets of Dynamic Ideas were sold to American Express. He is also the founder of Dynamic Ideas Press, a publisher of scientific books, the cofounder of Benefits Science, a company that designs health care plans for companies, of Dynamic Ideas Financial, a company that provides financial advice to customers, of Alpha Dynamics, an asset management company, P2 Analytics, an analytics consulting company and of MyA health, a personalized health care advice company. Bertsimas has coauthored more than 200 scientific papers. Bertsimas holds a BS in electrical engineering and computer science from the National Technical University of Athens, Greece, as well as an MS in operations research and a PhD in applied mathematics and operations research from MIT.

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Hi, my name is Harry Bondi and I'm a position at MIT in this video. I'll give you an introduction to my work with my advisor. Trucks, that Democrats voting on optimizing in and out box in composition. The season few world in Flames. I the highly contagious respiratory disease that affects about 5 to 15% of the world's population causing up to $650,000 annual deaths worldwide First line of defense against flu virus is the flu vaccine strains. The Roxy needs to be reformulated every year

for the more the vaccine needs to be prepared. At least six to eight months in advance of the flu season 3 pound for vaccine production and distribution across the world. The problem resolved here is twofold first to credit strains that are expected to be prevalent in an upcoming flu season. And then optimize the vaccine composition play Chief protective effect against flu. The historical prevalence of wild strains are available in the form of a three-dimensional cancer representing problems of weighted trains across

different locations. And time. Mostly populated because of the fact that somebody is Phantom mist or not. Observed, during testing and secondly during every flu season, Deadpool. When he was a tense of completion model to predict while strength that are expected to be prevalent in the future, we can describe the traits of circulation. I am strange for not coming to season. Using the concert in tea set, the tablet, the robots, prescriptive problem, to optimize the

flu vaccine composition, please report wallpaper for more details on this. 4D result, Singapore, be conducted a retrospective study 12. G of the boxing compositions betraying a predictive model difficulty of the vaccine, composition in terms of morbidity and mortality rates. In this figure, we show a comparison of morbidity rates countries in the northern hemisphere using boxing, compositions proposed by the World Health Organization, little basket on an average,

we observe about 11 to 14 per cent increase in Marble deteriorate, using the Rope aspect of the backseat. In the second figure to be sure similar comparison. But now on mortality rate again, we observed about a 11% decrease in. Mortality, please refer to a push lawn mower motor Visa dance to thank you.

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Hari Bandi
Dimitris Bertsimas